Routes are a big part of an Airline. It is important to configure them properly!
Go to the Crew Portal and select "Routes" under the Administration section.
In this page you can see all your VA routes
Create a route by clicking on the "Add a route" button and fill in the route details in the following modal
Click the Edit (6) button on any route to open the edit modal
When edditing a route you can tick/untick the "Enable route?" option to enable or disable the route.
Disabled routes will not show up on the Route Browser, the route map or when trying to fetch one from the FB Flight Plan. XP is also not rewarded for disabled routes.
Click the Delete (7) button on a route to completely remove it from your VA.